Before the Spring/Summer 2022 show began, Versace had a team of shirtless muscle men come out and take their positions by a series of thick ropes. The men pulled and pulled throughout the runway to keep the baroque canopies billowing.

Once the lights finally came up, Dua Lipa stepped out in a black set, complete with brightly colored safety pins holding her skirt together as her song "Physical" set the rhythm of the spirited runway show. The dark aesthetic continued on the models behind her, before eventually turning to highlighter shades of purple, green, pink, and so on. Chainmail dresses and monochrome suits closed the show, accessorized with chunky heels and pastel tights.

A number of recognizable faces walked, all to the soundtrack of a pop medley. Gigi Hadid, Emily Ratajkowski, and Adriana Lima were all present. Most notably, Naomi Campbell herself, who has had a longstanding relationship with the brand, made an appearance.

Once the final walkthrough commenced, Donatella Versace came out for her bow in skin-tight latex, arm in arm with Lipa wearing the finale piece: a bright pink, slinky gown.