Beautiful Virgin Islands


Study reveals cancer’s ‘infinite’ ability to evolve

Study reveals cancer’s ‘infinite’ ability to evolve

An unprecedented analysis of how cancers grow has revealed an "almost infinite" ability of tumours to evolve and survive, say scientists.

The results of tracking lung cancers for nine years left the research team "surprised" and "in awe" at the formidable force they were up against.

They have concluded we need more focus on prevention, with a "universal" cure unlikely any time soon.

Cancer Research UK said early detection of cancer was vitally important.

The study - entitled TracerX - provides the most in-depth analysis of how cancers evolve and what causes them to spread.

Cancers change and evolve over time - they are not fixed and immutable. They can become more aggressive: better at evading the immune system and able to spread around the body.

A tumour starts as a single, corrupted cell, but becomes a mixture of millions of cells that have all mutated in slightly different ways.

TracerX tracked that diversity and how it changes over time inside lung cancer patients and say the results would apply across different types of cancer.

"That has never been done before at this scale," said Prof Charles Swanton, from the Francis Crick Institute and University College London.

More than 400 people - treated at 13 hospitals in the UK - had biopsies taken from different parts of their lung cancer as the disease progressed.

"It has surprised me how adaptable tumours can be," Prof Swanton told me.

"I don't want to sound too depressing about this, but I think - given the almost infinite possibilities in which a tumour can evolve, and the very large number of cells in a late-stage tumour, which could be several hundred billion cells - then achieving cures in all patients with late-stage disease is a formidable task."

Prof Charles Swanton says challenge of tumours evolving inside our body means we need to focus on preventing cancer.


Prof Swanton said: "I don't think we're going to be able to come up with universal cures.

"If we want to make the biggest impact we need to focus on prevention, early detection and early detection of relapse."

Obesity, smoking, alcohol and poor diet all increase the risk of some cancers. Tackling inflammation in the body is also being seen as a way of preventing cancer. Inflammation is the likely explanation for air pollution causing lung cancers and inflammatory bowel disease increasing the risk of colon cancer.

The evolutionary analysis has been published across seven separate studies in the journals Nature and Nature Medicine.

The research showed:

* Highly aggressive cells in the initial tumour are the ones that ultimately end up spreading around the body

* Tumours showing higher levels of genetic "chaos" were more likely to relapse after surgery to other parts of the body

* Analysing blood for fragments of tumour DNA meant signs of it returning could be spotted up to 200 days before appearing on a CT scan

* The cellular machinery that reads the instructions in our DNA can become corrupted in cancerous cells making them more aggressive.

The researchers hope the findings could, in the future, help them predict how a patient's tumour will spread and to tailor treatment.

Dr David Crosby, the head of prevention and early detection at Cancer Research UK, said: "The exciting results emerging from TracerX improve our understanding that cancer is a disease which evolves as it progresses, meaning that late-stage cancers can become very hard to treat successfully.

"This underscores the crucial importance of further research to help us to detect cancers at the earliest stages of their development or even better, to prevent them from happening at all."

Comments

Oh ya 1 year ago
You will be reading a lot more stories about cancer in the future as it has now been noted and proven the the bio weapon that they called the vaccine is causing turbo cancer. Stop taking any shots for anything, your life might depend on it

Newsletter

Related Articles

Beautiful Virgin Islands
0:00
0:00
Close
Upcoming Pandemic Inevitable, Warns Former UK Chief Scientific Advisor
I have a dream, MLK inspiring speech
British Tourists Assaulted by Bouncers in Pattaya, Thailand
Aretha Franklin, Marvis Staples - Oh Happy Day
Facebook Delays Removal of Fake Account Exploiting TikTok Star
BVI Freedom Song
Billionaire Non-Domicile Flees UK Amid Tax Law Changes
Billy Preston - You Can't Beat God Giving (Live)
Nicki Minaj's Manchester Concert Canceled After Amsterdam Arrest
VIRGIN ISLANDS REGGAE CARIBBEAN RIDDIMZ
UK Conservative Party Proposes Mandatory National Service at 18
Oh Happy Day Edwin Hawkins - Anthony Brown w FBCG Combined Choir
Kate Middleton's Public Absence Throughout 2024
'Stand by Me' performed by Karen Gibson and The Kingdom Choir
Asylum Seekers Arriving In UK by Sea Exceed 10,000 This Year
National Anthem of the British Virgin Islands - Oh, Beautiful Virgin
UK Criticizes ICJ Order on Israel's Rafah Assault
Hello Dolly
Ukraine's Fight Against Corruption Gains Ground Amid War
for KING & COUNTRY - Amen (Reborn) [feat. Lecrae & The WRLDFMS Tony Wi
Czech President Petr Pavel Injured in Motorcycle Accident
Bob Marley - Get Up Stand Up
Record Number of Abortions in England and Wales
Yes He Can
Paul McCartney Honours Bruce Springsteen at Ivor Novello Awards
What A Friend We Have In Jesus
US and UK to Reject ICJ Ruling on Israel's Rafah Offensive
Unforgettable
World Court Orders Immediate Halt to Israeli Offensive in Gaza
Touch The Hem Of His Garment
Understanding FLiRT COVID Variants and Their Impact
The Lord's Prayer
Baltic NATO Members to Construct 'Drone Wall'
THE GOD MOVEMENT...BEAUTIFUL BVI
Global Life Expectancy Dropped By 2 Years Due To COVID-19
Siyahamba
Macron Halts New Caledonia Voting Reform After Riots
Ray Charles And The Voices Of Jubilaton, Oh, Happy Day
Rishi Sunak Shelves Rwanda and Smoking Policies Ahead of Election
Ramblin' Rose
US Refuses World Court Jurisdiction
Protoje - Who Knows ft. Chronixx
China Conducts Surprise Military Drills Around Taiwan
Pressure - Virgin Islands Nice
Grim Polls Predict Major Loss for PM Rishi Sunak
Phil Wickham - House Of The Lord
Rishi Sunak's Campaign for UK Election: Key Issues Highlighted
My God Is Real (Yes, God Is Real)
German Property Crisis Worsens as Foreign Investment Declines
The Lion King Circle of Life by LEBO M. — LIVE at the HAVASI Symphonic
Princess of Wales's Taskforce Calls for Business Investment in Early Childhood
Louis Armstrong - When The Saints Go Marching In
Campaign Groups Condemn UK Report on Protests
Kanye West Sunday Service - hallelujah, salvation, and glory
Former Royal Marine Charged with Espionage Found Dead
Jonathan Nelson - I Believe (Island Medley
Australian PM Calls for Julian Assange's Freedom
From The Virgin Islands Sqad Up
ICC Seeks Arrest Warrants for Israeli and Hamas Leaders
Common, John Legend - Glory
UK's Infected Blood Scandal: Conclusion Nears After Seven Years
Anthony Evans vs. Jesse Campbell - If I Ain't Got You
Julian Assange Granted Right to Challenge US Extradition
I have a dream, MLK inspiring speech
Congo Army Thwarts Attempted Coup Involving Americans and a British Citizen
Aretha Franklin, Marvis Staples - Oh Happy Day
Ireland's Homeless Gain Voting Rights
BVI Freedom Song
Blinken orders crackdown on Israel-Hamas leaks
Billy Preston - You Can't Beat God Giving (Live)
Julian Assange Faces US Extradition: Key Facts
VIRGIN ISLANDS REGGAE CARIBBEAN RIDDIMZ
Jacob Zuma Takes Campaign to ANC Stronghold Soweto
Oh Happy Day Edwin Hawkins - Anthony Brown w FBCG Combined Choir
Attempted Assassination of Slovakia PM Robert Fico: Investigation Ongoing
'Stand by Me' performed by Karen Gibson and The Kingdom Choir
What Happens If an Iranian President Dies in Office?
National Anthem of the British Virgin Islands - Oh, Beautiful Virgin
Spain Recalls Ambassador After Argentina President's Remarks
Hello Dolly
Rishi Sunak Faces Cabinet Backlash Over Proposed Changes to Foreign Student Visas
for KING & COUNTRY - Amen (Reborn) [feat. Lecrae & The WRLDFMS Tony Wi
Rwanda Denies Entry to Human Rights Researcher
Bob Marley - Get Up Stand Up
Iranian President Ebrahim Raisi Reportedly Killed in Helicopter Crash
Yes He Can
Blue Origin Resumes Space Tourism with 90-Year-Old Ed Dwight
What A Friend We Have In Jesus
Rishi Sunak and Wife Akshata Murty Wealthier Than King Charles
Unforgettable
New Dutch Government Drives Wedge Through EU Liberals
Touch The Hem Of His Garment
Iranian President Raisi Missing After Helicopter Goes Down
The Lord's Prayer
Freemasons and ‘Global War Party’ Accused of Conspiring Against Georgia
THE GOD MOVEMENT...BEAUTIFUL BVI
Poland Supports Rolls-Royce's Nuclear Power Plant Initiative
Siyahamba
European Ports Overflow with Unsold Electric Vehicles
Ray Charles And The Voices Of Jubilaton, Oh, Happy Day
×