Beautiful Virgin Islands

Wednesday, Sep 17, 2025

The Bill & Melinda Gates Foundation partly funded an Omicron variant study with a surprising conclusion about boosters

The Bill & Melinda Gates Foundation partly funded an Omicron variant study with a surprising conclusion about boosters

The latest Omicron subvariant may be a master at evading the immune response our bodies produce from the vaccine or previous COVID-19 infection, but a new study suggests existing booster shots will still help.
Getting a booster can generate enough of an antibody response and protection from severe disease outcomes to hold up against any of the new Omicron subvariants, according to an early release paper published this week in Science. That extends to BA.5, now the most prevalent COVID strain in the U.S. and a driver of COVID-19 reinfections across the country.

The finding comes as the Biden administration considers whether to expand access to a second booster shot to all adults because of concerns that subvariants BA.4 and BA.5 will further push up cases and hospitalizations. Since March, anyone 50 and older or immunocompromised and at least 12 years old has been eligible for a second booster, per CDC recommendations.

Led by the University of Washington School of Medicine’s Veesler Lab, the research team started a few months ago by just looking at the previously dominant BA.1, BA.2, and BA.2.12.1 subvariants, then later adding in BA.4 and BA.5. It assessed the properties of these subvariants and evaluated how a panel of seven vaccines already available in the U.S. and around the globe would protect against them.

BA.5 is a relatively new Omicron subvariant but “probably the most important one now in the study as it’s about to become globally dominant,” according to John Bowen, one of the paper’s lead authors and a biochemist at the Veesler Lab.

The BA.5 strain has been touted as the most contagious one yet, so much so that vaccinated people have reported catching it even after a recent bout of COVID-19. The first part of the study sheds light on why that is; BA.5 can outcompete other subvariants because its spike protein binds to the host receptor more than six times better than the original strain that first circulated in 2019.

The researchers ultimately determined that BA.5 will be the most immune-evasive COVID-19 variant to date, but that doesn’t mean our previous boosters can no longer restore protection.

“We were able to look at essentially every single prominent vaccine platform in the world side by side and see that despite the scariness of this variant, all of these vaccine platforms are going to elicit solid immune responses,” Bowen told Fortune.

Because of BA.5’s reputation, the findings initially caught the researcher by surprise.

“When I was seeing the data after the third shot, I had to repeat it over and over again because I was just like, ‘Why am I not seeing that this is as immune evasive as other people have said?’” Bowen recounted. “We were very excited to see that even though it’s more immune evasive than the other ones we tested, previous methods are still going to protect against it.”

The research effort was an international collaboration between infectious disease research physicians and scientists from UW Medicine, the Fred Hutchinson Cancer Center in Seattle, and institutes in California, Argentina, Italy, Pakistan, and Switzerland. It received funding from a plethora of sources, including the Bill & Melinda Gates Foundation and the National Institute of Allergy and Infectious Diseases.

The Food and Drug Administration has advised vaccine makers to update their booster shots to target the BA.4 and BA.5 Omicron subvariants. While people wait for those, though, Bowen said the research indicates that vaccines designed for a strain from a few years ago still work.

“We totally agree it’s very important to continue trying to find better ways to make protective vaccines,” he said. “It’s going to take some time to get those. If people need vaccines, we know that current boosting methods are going to be protective.”
Newsletter

Related Articles

Beautiful Virgin Islands
0:00
0:00
Close
Hong Kong Industry Group Calls for HK$20 Billion Support Fund to Ease Property Market Stress
Joe Biden’s Post-Presidency Speaking Fees Face Weak Demand amid Corporate Reluctance
Charlie Kirk's murder will break the left's hateful cancel tactics
Kash Patel erupts at ‘buffoon’ Sen. Adam Schiff over Russiagate: ‘You are the biggest fraud’
Homeland Security says Emmy speech ‘fanning the flames of hatred’ after Einbinder’s ‘F— ICE’ remark
Charlie Kirk’s Alleged Assassin Tyler Robinson Faces Death Penalty as Charges Formally Announced
Actor, director, environmentalist Robert Redford dies at 89
The conservative right spreads westward: a huge achievement for 'Alternative for Germany' in local elections
JD Vance Says There Is “No Unity” with Those Who Celebrate Charlie Kirk’s Killing, and he is right!
Trump sues the 'New York Times' for an astronomical sum of 15 billion dollars
Florida Hospital Welcomes Its Largest-Ever Baby: Annan, Nearly Fourteen Pounds at Birth
U.S. and Britain Poised to Finalize Over $10 Billion in High-Tech, Nuclear and Defense Deals During Trump State Visit
China Finds Nvidia Violated Antitrust Laws in Mellanox Deal, Deepens Trade Tensions with US
US Air Force Begins Modifications on Qatar-Donated Jet Amid Plans to Use It as Air Force One
Pope Leo Warns of Societal Crisis Over Mega-CEO Pay, Citing Tesla’s Proposed Trillion-Dollar Package
Poland Green-Lights NATO Deployment in Response to Major Russian Drone Incursion
Elon Musk Retakes Lead as World’s Richest After Brief Ellison Surge
U.S. and China Agree on Framework to Shift TikTok to American Ownership
London Daily Podcast: London Massive Pro Democracy Rally, Musk Support, UK Economic Data and Premier League Results Mark Eventful Weekend
This Week in AI: Meta’s Superintelligence Push, xAI’s Ten Billion-Dollar Raise, Genesis AI’s Robotics Ambitions, Microsoft Restructuring, Amazon’s Million-Robot Milestone, and Google’s AlphaGenome Update
Le Pen Tightens the Pressure on Macron as France Edges Toward Political Breakdown
Musk calls for new UK government at huge pro-democracy rally in London, but Britons have been brainwashed to obey instead of fighting for their human rights
Elon Musk responds to post calling for the murder of Erika Kirk, widow of Charlie Kirk: 'Either we fight back or they will kill us'
Czech Republic signs €1.34 billion contract for Leopard 2A8 main battle tanks with delivery from 2028
USA: Office Depot Employees Refused to Print Poster in Memory of Charlie Kirk – and Were Fired
Proposed U.S. Bill Would Allow Civil Suits Against Judges Who Release Repeat Violent Offenders
Penske Media Sues Google Over “AI Overviews,” Claiming It Uses Journalism Without Consent and Destroys Traffic
Indian Student Engineers Propose “Project REBIRTH” to Protect Aircraft from Crashes Using AI, Airbags and Smart Materials
French Debt Downgrade Piles Pressure on Macron’s New Prime Minister
US and UK Near Tech, Nuclear and Whisky Deals Ahead of Trump Trip
One in Three Europeans Now Uses TikTok, According to the Chinese Tech Giant
Could AI Nursing Robots Help Healthcare Staffing Shortages?
NATO Deploys ‘Eastern Sentry’ After Russian Drones Violate Polish Airspace
Anesthesiologist Left Operation Mid-Surgery to Have Sex with Nurse
Tens of Thousands of Young Chinese Get Up Every Morning and Go to Work Where They Do Nothing
The New Life of Novak Djokovic
The German Owner of Politico Mathias Döpfner Eyes Further U.S. Media Expansion After Axel Springer Restructuring
Suspect Arrested: Utah Man in Custody for Charlie Kirk’s Fatal Shooting
In a politically motivated trial: Bolsonaro Sentenced to 27 Years for Plotting Coup After 2022 Defeat
German police raid AfD lawmaker’s offices in inquiry over Chinese payments
Turkish authorities seize leading broadcaster amid fraud and tax investigation
Volkswagen launches aggressive strategy to fend off Chinese challenge in Europe’s EV market
ChatGPT CEO signals policy to alert authorities over suicidal youth after teen’s death
The British legal mafia hit back: Banksy mural of judge beating protester is scrubbed from London court
Surpassing Musk: Larry Ellison becomes the richest man in the world
Embarrassment for Starmer: He fired the ambassador photographed on Epstein’s 'pedophile island'
Manhunt after 'skilled sniper' shot Charlie Kirk. Footage: Suspect running on rooftop during panic
Effective Protest Results: Nepal’s Prime Minister Resigns as Youth-Led Unrest Shakes the Nation
Qatari prime minister says Netanyahu ‘killed any hope’ for Israeli hostages
King Charles and Prince Harry Share First In-Person Moment in 19 Months
×