Beautiful Virgin Islands

Friday, Aug 08, 2025

Moderna Submits Application Before US Regulator For Covid Booster Shot

Moderna Submits Application Before US Regulator For Covid Booster Shot

The third shot of the Moderna vaccine, known as mRNA-1273, was given to 344 participants in a study six months after their second dose.
Moderna on Wednesday announced it had begun submitting an application to the US Food and Drug Administration to authorize a booster of its Covid vaccine after trial data showed a significant increase in antibodies against variants.

The third shot of the vaccine, known as mRNA-1273, was given to 344 participants in a study six months after their second dose.

The first two doses were 100 micrograms, while the booster was half that at 50 micrograms.

An analysis showed the booster increased neutralizing antibody levels against variants of concern, including Delta by more than 42.3-fold, Gamma by 43.6-fold, and Beta by 32-fold, with similar gains seen across age groups including over-65s.

Ultra-contagious Delta, first identified in India, is now the dominant strain globally.

"We remain committed to staying ahead of the virus and following the evolving epidemiology of SARS-CoV-2," Stephane Bancel, the company's CEO, said in a statement.

The company said it was also planning submissions to the European Medicines Agency (EMA) and other regulatory authorities in the coming days.

While Moderna is submitting data for a repetition of its first vaccine, which was developed against the original strain first identified in Wuhan, China, the company has previously tested a variant-specific booster against Beta, which was first identified in South Africa but has faded considerably in recent months.

US President Joe Biden's administration has begun offering third Covid vaccine doses to immunocompromised people and plans to widen boosters to everyone eligible, eight months after their second dose, starting September 20.

That decision has left many health experts baffled, because although there is evidence that vaccine efficacy is waning against infection, it has remained largely stable against hospitalization and deaths -- the purpose for which the shots were conceived.

The move has also been criticized on the basis that most developing countries at this time don't even have enough vaccines to give their populations their first or second doses.

Beyond the questionable ethics and politics of failing to provide vaccines to poor countries, leaving these regions under-vaccinated for a prolonged period of time risks incubating new and possibly more dangerous variants that could evade the protective action of the current generation of vaccines.

Also on Wednesday, the FDA announced it would hold a meeting on September 17 to evaluate whether to authorize a third booster dose of Pfizer's mRNA Covid shot.
Newsletter

Related Articles

Beautiful Virgin Islands
0:00
0:00
Close
Trump Administration Increases Reward for Arrest of Venezuelan President Maduro to Fifty Million Dollars
Armenia and Azerbaijan to Sign US-Brokered Framework Agreement for Nakhchivan Corridor
British Labour Government Utilizes Counter-Terrorism Tools for Social Media Monitoring Against Legitimate Critics
OpenAI Launches GPT‑5, Its Most Advanced AI Model Yet
Embarrassment in Britain: Homelessness Minister Evicted Tenants and Forced to Resign
President Trump nominated Stephen Miran, his top economic adviser and a critic of the Federal Reserve, to temporarily fill an open Fed seat
The AI-Powered Education Revolution: Market Potential and Transformative Impact
Chikungunya Virus Outbreak in Southern China: Over 7,000 Hospitalized
French wine makers have seen catastrophic damage to vines that were almost ready to be harvested after the worst fires in more than 70 years burned through the south of the country
US Lawmaker Probes Intel CEO’s China Ties Amid National Security Concerns
Brazilian President Lula says he’ll contact the leaders of BRICS states to propose a unified response to U.S. tariffs
Trump Open to Meeting Putin as Soon as Next Week, with Possible Trilateral Summit Including Zelenskiy
Katy Perry and Justin Trudeau spark dating rumors, joining high stakes world of celeb-politician romances
US envoy Steve Witkoff arrived in Moscow to seek a breakthrough in the Ukraine war ahead of President Trump’s peace deadline
WhatsApp Deletes 6.8 Million Scam Accounts Amid Rising Global Fraud
Nine people have been hospitalized and dozens of salmonella cases have been reported after an outbreak of infections linked to certain brands of pistachios and pistachio-containing products, according to the Public Health Agency of Canada
Karol Nawrocki Inaugurated as Poland’s President, Setting Stage for Clash with Tusk Government
Trump Signals JD Vance as ‘Most Likely’ MAGA Successor for 2028
US Charges Two Chinese Nationals for Illegal Nvidia AI Chip Exports
Texas Residents Face Water Restrictions While AI Data Centers Consume Millions of Gallons
U.S. Tariff Policy Triggers Market Volatility Amid Growing Global Trade Tensions
Tariffs, AI, and the Shifting U.S. Macro Landscape: Navigating a New Economic Regime
Representative Greene Urges H-1B Visa Cuts Amid U.S.-India Trade Tensions
U.S. House Committee Subpoenas Clintons and Senior Officials in Epstein Investigation
Sydney Sweeney Registered as Republican as Controversial American Eagle Ad Sparks Debate
Trump Accuses Major Banks of Politically Motivated Account Denials and Prepares Executive Order
TikTok Removes Huda Kattan Video Over Anti-Israel Conspiracy Claims
Trump Threatens Tariffs on India Over Russian Oil Imports
German Finance Minister Criticizes Trump’s Attacks on Institutions
U.S. Proposes Visa Bond of Up to $15,000 for Some Applicants
U.S. Farmers Increase Lobbying Amid Immigration Crackdown
Elon Musk Receives $23.7 Billion Tesla Stock Award
Texas House Paralyzed After Democrats Walk Out Over Redistricting
Mexican Cartels Complicate Sheinbaum’s U.S. Security Talks
Mark Zuckerberg Declares War on the iPhone
India Rejects U.S. Tariff Threat, Defends Russian Oil Purchases
United States Establishes Strategic Bitcoin Reserve and Digital Asset Stockpile
Thousands of Private ChatGPT Conversations Accidentally Indexed by Google
China Tightens Mineral Controls, Curtailing Critical Inputs for Western Defence Contractors
OpenAI’s Bold Bet: Teaching AI to Think, Not Just Chat
Tesla Seeks Shareholder Approval for $29 Billion Compensation Package for Elon Musk
Nvidia is cutting prices on its RTX 50-series graphics cards after sales slowed and inventories piled up
Ghislaine Maxwell Transferred to Minimum-Security Prison Amid Ongoing DOJ Discussions
U.S. Tariffs Surge to Highest Levels in Nearly a Century Under Second Trump Term
Matt Taibbi Slams Media for Role in Russiagate Narrative
Pilots Call for Mental Health Support Without Stigma
All Five Trapped Miners Found Dead After El Teniente Mine Collapse
Ong Beng Seng Pleads Guilty in Corruption Case Linked to Former Singapore Transport Minister
BP’s Largest Oil and Gas Find in 25 Years Uncovered Offshore Brazil
Italy Fines Shein One Million Euros for Misleading Sustainability Claims
×